VHL Protein Pathway
created 18 Jun, 10:11 am · ⏱ built in 1m 40s · 👁 2 views
VHL is the cell’s oxygen sensor: when oxygen is present, it tags HIF-α for destruction, but in hypoxia or VHL loss, HIF builds up and turns on VEGF, PDGF, and EPO. Click the mode buttons to switch states, then tap each box to see what happens and which genes or clinical effects appear.
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Third Year Medical School Student
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